Diagnostic role of platelet indices and leukocyte count in pseudothrombocytopenia

Objective: This study aimed to evaluate whether platelet indices and leukocyte count predict the diagnosis of Ethylene Diamine Tetra Acetic Acid induced pseudothrombocytopenia (EDTA-PTCP) differ this entity from immune thrombocytopenia (ITP). Methods: One-hundred sixty-nine individuals (52 patients diagnosed with EDTA-PTCP, 52 newly ITP, 65 healthy individuals) were included. Demographic data complete blood (CBC) compared between groups retrospectively. Results: Age sex distribution similar in all groups. Between EDTA-PTCP ITP groups, no difference was found for absolute leukocyte, neutrophil, lymphocyte, monocyte counts as well hemoglobin level, red-cell width (RDW), (PDW). The median mean volume (MPV) group be higher than control (p<0.001 p=0.001, respectively, 95% confidence interval; 2.52-4.45 0.56-2.6). Conclusion: results support that low CBC may a false result due EDTA. Thrombocytopenic who have bleeding symptoms normal MPV should evaluated EDTA-PTCP. evaluation can made by peripheral smear or tube containing other anticoagulants EDTA (such citrate heparin). Therefore increase indicate rather To make more definite recommendation on issue, studies involving are needed.